Chevalone C
Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines.
For research use only. We do not sell to patients.
- CAS No.: 1318025-77-2
- Formula: C28H40O5
- Molecular Weight:456.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chevalone C (1, 10, 50, 100, 200 μM; 24 hours) exhibits a significant decrease of cell viability in HepG2, HCT116 and HT29 cell lines (ic50=153 μM, 190 μM, 98 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1318025-77-2
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Molecular Weight 456.61
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Formula C28H40O5
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SMILES
CC(OC1=C2C[C@@]3([C@@](C)(O1)CC[C@]4([C@]3(CC[C@@]5([C@@]4(CC[C@@H](C5(C)C)OC(C)=O)C)[H])C)[H])[H])=CC2=O
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Structure Classification
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Initial Source
Eurotium chevalieri
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sasiphimol Sawadsitang, et al. Antimalarial and cytotoxic constituents of Xylaria cf. cubensis PK108. Nat Prod Res. 2015;29(21):2033-6. [Content Brief]
[2]. M Prata-Sena, et al. Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells. Phytother Res. 2016 Nov;30(11):1862-1871. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chevalone C Related Classifications
HY-120607 Related Classifications
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