CJ-15208
CJ-15208 is a potent and selective κ-opioid receptor antagonist with significant opioid activity. CJ-15208 exhibited strong analgesic effects in the warm water tail withdrawal test in mice and was mediated through multiple opioid receptors. The stereoisomers of CJ-15208 exhibited different opioid activity characteristics, for example, one stereoisomer exhibited κ-opioid receptor antagonism, while the other exhibited δ-opioid receptor antagonism. All stereoisomers of CJ-15208 had no significant effects on respiration. The stereoisomers of CJ-15208 did not lead to the development of drug tolerance, which makes it potential in the further development of safe opioid analgesics.
For research use only. We do not sell to patients.
- CAS No.: 210236-47-8
- Formula: C34H35N5O4
- Molecular Weight:577.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 210236-47-8
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Molecular Weight 577.67
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Formula C34H35N5O4
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SMILES
O=C(N[C@H](C(N1[C@@](CCC1)([H])C(N[C@H](C(N2)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)[C@@H]2CC5=CNC6=CC=CC=C56
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CJ-15208 Related Classifications
HY-117881 Related Classifications
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