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Cat. No.: HY-184823

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CK2-IN-17

CK2-IN-17 is a protein kinase CK2 inhibitor with an IC₅₀ of 9.5 μM against human targets. CK2-IN-17 regulates the activity of protein kinase CK2 by interacting with its ATP-binding site. CK2-IN-17 can be used in studies related to protein kinase CK2-mediated pathways, such as tumors.

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CAS No.: 1417634-25-3
화학식: C₁₅H₁₇N₃O₄
분자량:303.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CK2-IN-17 Chemical Structure

CAS No.: 1417634-25-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

CK2

9.5 μM (IC₅₀)

All Casein Kinase Isoforms :

In Vitro

CK2-IN-17 (compound 21) inhibits recombinant human CK2 holoenzyme with an IC₅₀ of 9.5 μM in an in vitro kinase activity assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1417634-25-3
분자량 303.31
화학식 C₁₅H₁₇N₃O₄
SMILES

O=C1N=C(NC(CCCC)=C1)NC2=CC=C(C(C(O)=O)=C2)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Chekanov MO, et al. Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors. Journal of enzyme inhibition and medicinal chemistry. 2014 Oct;29(5):639-46. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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CK2-IN-17

All Casein Kinase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CK2-IN-17 Related Classifications

HY-184823 Related Classifications