Cl-PEG6-acid
Based on 1 Customer Validation
Cl-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2365309-92-6
- Formula: C14H27ClO8
- Molecular Weight:358.81
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2365309-92-6
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Appearance Liquid (Density: 1.181±0.06 g/cm3)
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Molecular Weight 358.81
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Formula C14H27ClO8
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Color Colorless to light yellow
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SMILES
OC(COCCOCCOCCOCCOCCOCCCl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (278.70 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7870 mL | 13.9350 mL | 27.8699 mL | 69.6748 mL |
| 5 mM | 0.5574 mL | 2.7870 mL | 5.5740 mL | 13.9350 mL | |
| 10 mM | 0.2787 mL | 1.3935 mL | 2.7870 mL | 6.9675 mL | |
| 15 mM | 0.1858 mL | 0.9290 mL | 1.8580 mL | 4.6450 mL | |
| 20 mM | 0.1393 mL | 0.6967 mL | 1.3935 mL | 3.4837 mL | |
| 25 mM | 0.1115 mL | 0.5574 mL | 1.1148 mL | 2.7870 mL | |
| 30 mM | 0.0929 mL | 0.4645 mL | 0.9290 mL | 2.3225 mL | |
| 40 mM | 0.0697 mL | 0.3484 mL | 0.6967 mL | 1.7419 mL | |
| 50 mM | 0.0557 mL | 0.2787 mL | 0.5574 mL | 1.3935 mL | |
| 60 mM | 0.0464 mL | 0.2322 mL | 0.4645 mL | 1.1612 mL | |
| 80 mM | 0.0348 mL | 0.1742 mL | 0.3484 mL | 0.8709 mL | |
| 100 mM | 0.0279 mL | 0.1393 mL | 0.2787 mL | 0.6967 mL |
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