Clascoterone-d6
Clascoterone-d6 (Cortexolone 17 alpha-propionate-d6) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.
For research use only. We do not sell to patients.
- Formula: C24H28D6O5
- Molecular Weight:408.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 19608-29-8
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Molecular Weight 408.56
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Formula C24H28D6O5
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SMILES
CCC(O[C@@]1(CC[C@]2([C@@]3(CC(C4=C(C(C([2H])(C[C@@]4([C@]3(CC[C@]12C)[H])C)[2H])=O)[2H])[2H])[H])[H])C(C([2H])(O)[2H])=O)=O
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Synonyms
Cortexolone 17 alpha-propionate-d6; Cortexolone 17α-propionate-d6; CB-03-01-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Trifu V, et al. Cortexolone 17伪-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0路05% cream. Br J Dermatol. 2011 Jul;165(1):177-83. [Content Brief]
[4]. Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54(12):881-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)