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Cat. No.: HY-N3993

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Clausine I

Clausine I is a natural alkaloid.

For research use only. We do not sell to patients.

CAS No.: 182261-94-5
Formula: C₁₄H₁₁NO₃
Molecular Weight:241.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Clausine I Chemical Structure

CAS No.: 182261-94-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Clausine I is a natural alkaloid.

Cellular Effect

Cell Line	Type	Value	Description	References
Vero	IC₅₀	>50 μM Compound: 4	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay	[PMID: 28094223]
Vero	IC₅₀	50 μM Compound: 4	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 72 hrs by tetrazolium dye assay	[PMID: 28094223]

In Vivo

Clausine I (0.2 mg/mL; 3-minute pre-incubation with platelets) significantly inhibited rabbit platelet aggregation induced by 100 μM arachidonic acid and 10 μg/mL collagen, but showed no clear inhibitory effect on platelet aggregation induced by 2 ng/mL platelet-activating factor^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 182261-94-5
Molecular Weight 241.24
Formula C₁₄H₁₁NO₃
SMILES

OC1=CC(C=O)=CC2=C1NC3=CC=C(OC)C=C23
Structure Classification
- Alkaloids
- Carbazole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu TS, et al. Carbazole alkaloids from Clausena excavata and their biological activity. Phytochemistry. 1996;43(1):133-140. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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