CLR1501
Based on 1 Customer Validation
CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound.
For research use only. We do not sell to patients.
- Purity: 98.62%
- CAS No.: 1250963-36-0
- Formula: C38H59BF2N3O4P
- Molecular Weight:701.67
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
CLR1501 exhibits five- to ninefold preferential uptake in these cancer cell lines in vitro compared to normal fibroblasts[1].
Excitation/emission peaks are 500/517 nm for CLR1501. CLR1501 exhibits tumor selectivity in vitro and in vivo for human glioblastoma stem-like (GSC) cell lines and xenografts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1250963-36-0
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Appearance Solid
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Molecular Weight 701.67
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Formula C38H59BF2N3O4P
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Color Brown to reddish brown
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SMILES
[F-][B+3]1([N-]2C(C(C3=CC=C(CCCCCCCCCCCCCCCCCCOP(OCC[N+](C)(C)C)([O-])=O)C=C3)=C4[N]1=CC=C4)=CC=C2)[F-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Weichert JP, et al. Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11;6(240):240ra75. [Content Brief]
[2]. Swanson KI, et al. Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection. Neurosurgery. 2015 Feb;76(2):115-23; discussion 123-4. [Content Brief]
[3]. Deming DA, Maher ME, Leystra AA, et al. Phospholipid ether analogs for the detection of colorectal tumors. PLoS One. 2014;9(10):e109668. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)