COX-1/2-IN-8
COX-1/2-IN-8 (compound 11f) is an orally active and potent inhibitor of COX-1 and COX-2, with IC50 values of 2.14 and 0.58 µM, respectively. COX-1/2-IN-8 displays a higher significant anti-inflammatory activity than Celecoxib (HY-14398).
For research use only. We do not sell to patients.
- Formula: C33H30N4OS
- Molecular Weight:530.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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COX-2 0.58 ± 0.0 μM (IC50) |
COX-1 2.14 ± 0.0 μM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 530.68
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Formula C33H30N4OS
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SMILES
O=C(C1=CC=CC=C1)CSC2=NN=C(C(N3CC4=C(C=CC=C4)CC3)C5=CC=CC=C5)N2C6=CC=C(C)C=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)