COX-2-IN-20
COX-2-IN-20 (Compound 5d) is a selective and orally active COX-2 inhibitor with an IC50 of 17.9 nM. COX-2-IN-20 shows anti-inflammatory activity.
For research use only. We do not sell to patients.
- CAS No.: 2529451-43-0
- Formula: C11H9ClFN3O2
- Molecular Weight:269.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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COX-2 17.9 nM (IC50) |
COX-1 19.3 μM (IC50) |
COX-2-IN-20 (Compound 5d) shows potential anti-inflammatory activity on NO inhibition in LPS-induced RAW 264.7 cell with an IC50 of 2.87 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2529451-43-0
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Molecular Weight 269.66
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Formula C11H9ClFN3O2
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SMILES
O=C(C1=NN(C2=CC=C(F)C=C2)C(CCl)=N1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2-IN-20 Related Classifications
HY-147809 Related Classifications
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