Creatine transporter-IN-1
Based on 1 Customer Validation
Creatine transporter-IN-1 is a synthetic creatine transporter (CT1/SLC6A8) inhibitor. Creatine transporter-IN-1 inhibits creatine uptake and shows anticancer activity against cancer cells.
For research use only. We do not sell to patients.
- Purity: 98.08%
- CAS No.: 1706435-74-6
- Formula: C5H9ClN4O2
- Molecular Weight:192.60
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Creatine transporter-IN-1 (Compound 4) (500 μM) weakly inhibits creatine uptake in CT1-expressing HEK293 cells[1].
Creatine transporter-IN-1 (0.1-100 μM; 24-48 h) reduces the viability of DLD-1 human colorectal adenocarcinoma cells in a concentration-dependent manner[1].
Creatine transporter-IN-1 (0.1-100 μM; 24-72 h) reduces the viability of HT-29 human colorectal adenocarcinoma cells in a concentration-dependent manner[1].
Creatine transporter-IN-1 (0.1-1 mM; 48 h) reduces the viability of MDA-MB-231 human breast adenocarcinoma cells in a concentration-dependent manner at millimolar concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human colorectal adenocarcinoma DLD-1 cells
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Concentration:0.1, 1, 10, 50, 100 μM
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Incubation Time:24 h; 48 h
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Result:Induced a concentration-dependent decrease in cell viability.
Decreased viability to approximately 80% of control levels at 100 μM after both 24 h and 48 h.
Caused statistically significant reductions at 10, 50, and 100 μM.
Chemical Information
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CAS No. 1706435-74-6
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Appearance Solid
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Molecular Weight 192.60
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Formula C5H9ClN4O2
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Color Light yellow to yellow
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SMILES
O=C(C1=CN(CCN)N=N1)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Creatine transporter-IN-1 Related Classifications
HY-W695425 Related Classifications
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- Creatine transporter-IN-1
- 1706435-74-6
- Amino acid Transporter
- HEK293 cells
- DLD-1 human colorectal adenocarcinoma cells
- HT-29 human colorectal adenocarcinoma cells
- colorectal adenocarcinoma
- CT1/SLC6A8
- creatine transporter
- MDA-MB-231 human breast adenocarcinoma cells
- breast adenocarcinoma
- Inhibitor
- inhibitor
- inhibit