crizotinib impurity 1
Based on 1 Customer Validation
Crizotinib impurity 1 is an impurity of Crizotinib (HY-50878).
For research use only. We do not sell to patients.
- Purity: 99.58%
- CAS No.: 877397-70-1
- Formula: C13H9Cl2FN2O3
- Molecular Weight:331.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 877397-70-1
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Appearance Solid
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Molecular Weight 331.13
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Formula C13H9Cl2FN2O3
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SMILES
FC1=C(C([C@@H](C)OC2=C([N+]([O-])=O)N=CC=C2)=C(Cl)C=C1)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (302.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (250 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0200 mL | 15.0998 mL | 30.1996 mL | 75.4990 mL |
| 5 mM | 0.6040 mL | 3.0200 mL | 6.0399 mL | 15.0998 mL | |
| 10 mM | 0.3020 mL | 1.5100 mL | 3.0200 mL | 7.5499 mL | |
| 15 mM | 0.2013 mL | 1.0067 mL | 2.0133 mL | 5.0333 mL | |
| 20 mM | 0.1510 mL | 0.7550 mL | 1.5100 mL | 3.7750 mL | |
| 25 mM | 0.1208 mL | 0.6040 mL | 1.2080 mL | 3.0200 mL | |
| 30 mM | 0.1007 mL | 0.5033 mL | 1.0067 mL | 2.5166 mL | |
| 40 mM | 0.0755 mL | 0.3775 mL | 0.7550 mL | 1.8875 mL | |
| 50 mM | 0.0604 mL | 0.3020 mL | 0.6040 mL | 1.5100 mL | |
| 60 mM | 0.0503 mL | 0.2517 mL | 0.5033 mL | 1.2583 mL | |
| 80 mM | 0.0377 mL | 0.1887 mL | 0.3775 mL | 0.9437 mL | |
| 100 mM | 0.0302 mL | 0.1510 mL | 0.3020 mL | 0.7550 mL |