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製品番号: HY-N9095

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Curculigoside C

Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 851713-74-1
分子式: C₂₂H₂₆O₁₂
分子量:482.43

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Curculigoside C 構造式

CAS 番号: 851713-74-1

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Curculigoside C displays neuroprotective effect in the evaluation of salvaging SY5Y cell death induced by H₂O₂^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Curculigoside C (15, 30 and 60 mg/kg) exhibits rapid oral absorption (T_max = 0.106 h, 0.111 h, and 0.111 h, respectively), high elimination (t_1/2 = 2.022 h, 2.061 h, and 2.048 h, respectively) and low absolute bioavailability (2.01%, 2.13%, and 2.39%, respectively)^[2].
Pharmacokinetic parameters of CC in rat plasma after intragastric administration^[1].

Dose (mg/kg)	t_1/2 (h)	AUC_0-60 (μg/L/h)	AUC_0-∞ (μg/L/h)	F (%)	Vd (L/kg)	CL_z (L/h/kg)
15	2.022 ± 0.184	0.106 ± 0.149	62.731 ± 10.149	66.310 ± 10.563	2.01	673.157 ± 116.509	231.036 ± 36.69
30	2.061 ± 0.325	0.111 ± 0.043	133.17 ± 48.434	140.656 ± 48.335	2.13	722.605 ± 316.306	234.188 ± 74.864
60	2.048 ± 0.227	0.111 ± 0.043	299.155 ± 80.954	316.980 ± 91.704	2.39	585.344 ± 124.289	201.905 ± 55.193
2.0 (i.v)	1.153 ± 0.203	-	416.700 ± 70.401	420.700 ± 70.690	-	8.122 ± 1.973	4.869 ± 0.834

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 851713-74-1
分子量 482.43
分子式 C₂₂H₂₆O₁₂
SMILES

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(C=CC(O)=C2)=C2COC(C3=C(C(O)=CC=C3OC)OC)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (277 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Wu Q, et al. Antioxidative phenols and phenolic glycosides from Curculigo orchioides. Chem Pharm Bull (Tokyo). 2005 Aug;53(8):1065-7. [Content Brief]

[2]. Di Wu, et al. Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS. Molecules. 2018 Dec 21;24(1):21. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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