D-2-Phosphoglyceric acid
D-2-Phosphoglyceric acid is an intermediate product of glycolysis and gluconeogenesis, and its level changes are associated with the glycolysis pathway regulated by MCT4. The intracellular level of D-2-Phosphoglyceric acid decreases in hypoxic glioblastoma stem cells after MCT4 knockdown. D-2-Phosphoglyceric acid can be used in the research of glioblastoma.
For research use only. We do not sell to patients.
- CAS No.: 3443-57-0
- Formula: C3H7O7P
- Molecular Weight:186.06
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
In Vitro
D-2-Phosphoglyceric acid (36 h) has significantly decreased intracellular levels in hypoxic E27 glioblastoma stem cells with MCT4 depletion, as a key glycolytic intermediate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 3443-57-0
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Molecular Weight 186.06
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Formula C3H7O7P
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SMILES
O=P(O)(O)O[C@H](CO)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D-2-Phosphoglyceric acid Related Classifications
HY-128736B Related Classifications
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