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Cat. No.: HY-128736B

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D-2-Phosphoglyceric acid

D-2-Phosphoglyceric acid is an intermediate product of glycolysis and gluconeogenesis, and its level changes are associated with the glycolysis pathway regulated by MCT4. The intracellular level of D-2-Phosphoglyceric acid decreases in hypoxic glioblastoma stem cells after MCT4 knockdown. D-2-Phosphoglyceric acid can be used in the research of glioblastoma.

For research use only. We do not sell to patients.

CAS No.: 3443-57-0
Formula: C₃H₇O₇P
Molecular Weight:186.06

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

D-2-Phosphoglyceric acid Chemical Structure

CAS No.: 3443-57-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

All Endogenous Metabolite Isoforms :

All Monocarboxylate Transporter Isoforms :

In Vitro

D-2-Phosphoglyceric acid (36 h) has significantly decreased intracellular levels in hypoxic E27 glioblastoma stem cells with MCT4 depletion, as a key glycolytic intermediate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3443-57-0
Molecular Weight 186.06
Formula C₃H₇O₇P
SMILES

O=P(O)(O)O[C@H](CO)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Al Shboul S, et al. Selective regulation and cellular metabolism by the lactate transporter MCT4 in GBM. Med Oncol. 2025;42(11):497. Published 2025 Sep 26. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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D-2-Phosphoglyceric acid

All Endogenous Metabolite Isoforms

All Monocarboxylate Transporter Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

D-2-Phosphoglyceric acid Related Classifications

HY-128736B Related Classifications