1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. DC4

DC4 

Cat. No.: HY-135125
Handling Instructions

DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer.

For research use only. We do not sell to patients.

DC4 Chemical Structure

DC4 Chemical Structure

CAS No. : 615538-48-2

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Description

DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer[1].

In Vitro

DC4 can be conjugated to the humanized monoclonal antibody huB4 and huC242 by a linker SPP, SPDB, and SMCC to form huB4-SPP-DC44, huC242-SPDB-DC4, huC242-SPP-DC4, and huC242-SMCC-DC4[1].

Molecular Weight

718.12

Formula

C₃₄H₂₉ClN₅O₇PS

CAS No.

615538-48-2

SMILES

O=C(C(N1)=CC2=C1C=CC(NC(CCS)=O)=C2)NC3=CC4=C(NC(C(N5C[[email protected]@H](CCl)C6=C5C=C(OP(O)(O)=O)C7=CC=CC=C67)=O)=C4)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

DC4DC 4DC-4ADC CytotoxinPhosphateprodrugcytotoxicDNAalkylatorcancertargetedtreatmenthuB4huC242SPPSPDBSMCChuB4-SPP-DC44huC242-SPDB-DC4huC242-SPP-DC4huC242-SMCC-DC4Inhibitorinhibitorinhibit

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