Biotin-PEG3-propionic hydrazide
Based on 1 Customer Validation
Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
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- Reinheit: 98.0%
- CAS. Nr.: 1381861-94-4
- Formel: C19H35N5O6S
- Molecular Weight:461.58
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1381861-94-4
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Appearance Solid
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Molecular Weight 461.58
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Formel C19H35N5O6S
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Color White to off-white
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SMILES
O=C(NCCOCCOCCOCCC(NN)=O)CCCC[C@H]1[C@](NC2=O)([H])[C@](N2)([H])CS1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (216.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (239 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1665 mL | 10.8324 mL | 21.6647 mL | 54.1618 mL |
| 5 mM | 0.4333 mL | 2.1665 mL | 4.3329 mL | 10.8324 mL | |
| 10 mM | 0.2166 mL | 1.0832 mL | 2.1665 mL | 5.4162 mL | |
| 15 mM | 0.1444 mL | 0.7222 mL | 1.4443 mL | 3.6108 mL | |
| 20 mM | 0.1083 mL | 0.5416 mL | 1.0832 mL | 2.7081 mL | |
| 25 mM | 0.0867 mL | 0.4333 mL | 0.8666 mL | 2.1665 mL | |
| 30 mM | 0.0722 mL | 0.3611 mL | 0.7222 mL | 1.8054 mL | |
| 40 mM | 0.0542 mL | 0.2708 mL | 0.5416 mL | 1.3540 mL | |
| 50 mM | 0.0433 mL | 0.2166 mL | 0.4333 mL | 1.0832 mL | |
| 60 mM | 0.0361 mL | 0.1805 mL | 0.3611 mL | 0.9027 mL | |
| 80 mM | 0.0271 mL | 0.1354 mL | 0.2708 mL | 0.6770 mL | |
| 100 mM | 0.0217 mL | 0.1083 mL | 0.2166 mL | 0.5416 mL |
Biotin-PEG3-propionic hydrazide Related Classifications
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