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ISIS 329993

(Synonyms: ISIS-CRPRx)

ISIS 329993 (ISIS-CRPRx) is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis

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  • ISIS 329993 Chemical Structure
    ISIS 329993 Chemical Structure
CAS. Nr.: 827355-42-0
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  • ISIS 329993 Chemical Structure
    ISIS 329993 Chemical Structure DNA, d(P-thio)([2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]G-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]m5U-A-G-T-T-A-A-m5C-G-A-G-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5U-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C)
    1/16
  • DNA, d(P-thio)([2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]G-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]m5U-A-G-T-T-A-A-m5C-G-A-G-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5U-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C)