SILA-123
SILA-123 is a FLT3 inhibitor (FLT3-WT: IC50=2.1 nM; FLT3-ITD: IC50=1.0 nM). SILA-123 inhibits FLT3 phosphorylation and downstream signaling pathways, leading to apoptosis by arresting cell cycle progression at the G0/G1 phase. SILA-123 can be used in the study of acute myeloid leukemia.
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- CAS. Nr.: 2911585-37-8
- Formel: C24H25N5O2
- Molecular Weight:415.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2911585-37-8
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Molecular Weight 415.49
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Formel C24H25N5O2
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SMILES
CC1=NC2=C(C(N)=NO2)C(C3=CC=C(NC(NC4=CC=C(C(C)(C)C)C=C4)=O)C=C3)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SILA-123 Related Classifications
HY-162936 Related Classifications
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