TMC-205
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter.
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- CAS. Nr.: 403646-00-4
- Formel: C14H13NO2
- Molecular Weight:227.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Microbial Metabolite |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| HCT-116 | GI50 |
68 μM
Compound: 1, TMC-205
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Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
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[PMID: 25147604] |
Chemical Information
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CAS. Nr. 403646-00-4
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Molecular Weight 227.26
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Formel C14H13NO2
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SMILES
O=C(C1=CNC2=C1C=CC(/C=C/C(C)=C)=C2)O
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Structure Classification
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Initial Source
an unidentified fungus.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TMC-205 Related Classifications
HY-114646 Related Classifications
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