ABCG2-IN-1
ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice.
For research use only. We do not sell to patients.
- CAS No.: 2559759-40-7
- Formula: C26H36N4O4
- Molecular Weight:468.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.13 μM (ABCG2)[1]
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
52.2 μM
Compound: K2
|
Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 37482017] |
Chemical Information
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CAS No. 2559759-40-7
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Molecular Weight 468.59
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Formula C26H36N4O4
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SMILES
CC(C)C[C@H]1C2=C(C[C@]3([H])N1C([C@@H](NC3=O)CCC(NC(C)(C)C)=O)=O)C4=CC=C(OC)C=C4N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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