FC9402
Based on 2 publication(s) in Google Scholar
FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation.
For research use only. We do not sell to patients.
- Purity: 98.19%
- CAS No.: 2452401-65-7
- Formula: C19H16N4O
- Molecular Weight:316.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) FC9402
More
Biological Activity
SQOR[1]
FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2452401-65-7
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Appearance Solid
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Molecular Weight 316.36
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Formula C19H16N4O
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Color Light yellow to yellow
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SMILES
N#CC1=C(OC)N=C(C2=NC=CC=C2C)C=C1C3=CC=C(N)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Redox Biol
Knockout of the sulfide: quinone oxidoreductase SQR reduces growth of HCT116 tumor xenograft. [Abstract]2025 Apr 24:83:103650. PMID: 40305883 -
iScience
mCAUSE: Prioritizing mitochondrial targets that alleviate pancreatic cancer cell phenotypes. [Abstract]2024 Sep 3;27(9):110880. PMID: 39310760
Solvent & Solubility
DMSO : 100 mg/mL (316.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. WO 2020/146636 A1
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1610 mL | 15.8048 mL | 31.6096 mL | 79.0239 mL |
| 5 mM | 0.6322 mL | 3.1610 mL | 6.3219 mL | 15.8048 mL | |
| 10 mM | 0.3161 mL | 1.5805 mL | 3.1610 mL | 7.9024 mL | |
| 15 mM | 0.2107 mL | 1.0537 mL | 2.1073 mL | 5.2683 mL | |
| 20 mM | 0.1580 mL | 0.7902 mL | 1.5805 mL | 3.9512 mL | |
| 25 mM | 0.1264 mL | 0.6322 mL | 1.2644 mL | 3.1610 mL | |
| 30 mM | 0.1054 mL | 0.5268 mL | 1.0537 mL | 2.6341 mL | |
| 40 mM | 0.0790 mL | 0.3951 mL | 0.7902 mL | 1.9756 mL | |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6322 mL | 1.5805 mL | |
| 60 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3171 mL | |
| 80 mM | 0.0395 mL | 0.1976 mL | 0.3951 mL | 0.9878 mL | |
| 100 mM | 0.0316 mL | 0.1580 mL | 0.3161 mL | 0.7902 mL |
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