Copy Link Print Information

Omoprubart

(Synonyms: CAN-106)
Customer Review

Based on 1 Customer Validation

Omoprubart is an anti-C5 complement recombinant humanized monoclonal antibody. Omolubat can prevent C5 from cleaving into C5a and C5b, thereby inhibiting the formation and activation of the C5b-dependent membrane attack complex (MAC) on the surface of susceptible cells, leading to cell lysis (destruction). Omoprubart can be used for the study of paroxysmal nocturnal hemoglobinuria (PNH).

For research use only. We do not sell to patients.

  • Purity: 97.769%
  • CAS No.: 2763342-87-4
  • Molecular Weight:145.657 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Omoprubart
  • Experimental Validation Results for Omoprubart
  • Experimental Validation Results for Omoprubart
  • Omoprubart Chemical Structure
    Omoprubart Chemical Structure
CAS No.: 2763342-87-4
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Omoprubart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Keywords

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    IgG2-G4-kappa

  • 1/16

    Immobilized Complement C5 Protein, Human (HEK293, His, HY-P73396) can bind Omoprubart. The EC50 for this effect is 3.473 ng/mL.

  • 1/16

    Flow Cytometry analysis of HepG2 cells with Omoprubart (HY-P990753, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa(HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Omoprubart Chemical Structure
    1/16
  • Omoprubart
  • Immobilized Complement C5 Protein, Human (HEK293, His, HY-P73396) can bind Omoprubart. The EC50 for this effect is 3.473 ng/mL.
  • Flow Cytometry analysis of HepG2 cells with Omoprubart (HY-P990753, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa(HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG2-G4-kappa