SHR5133
SHR5133 is a highly potent, orally active HBV capsid assembly modulator. SHR5133 displays HBV DNA reduction (EC50=26.6 nM).
For research use only. We do not sell to patients.
- CAS No.: 2270943-23-0
- Formula: C19H18F4N6O2
- Molecular Weight:438.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
>100 μM
Compound: 22; SHR5133
|
Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer-glo assay
Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer-glo assay
|
[PMID: 35300087] |
Chemical Information
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CAS No. 2270943-23-0
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Molecular Weight 438.38
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Formula C19H18F4N6O2
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SMILES
O=C(C1=C2CN(C(NC3=CC=C(F)C(C#N)=C3)=O)[C@@H](C)CN2C=N1)N[C@H](C)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)