DEANO sodium
Based on 1 publication(s) in Google Scholar
DEANO sodium is notric oxide donor. DEANO sodium potentiates the abilitv of hypoxanthine/xanthine oxidase to induce lipid peroxidation as well as DNA single- and double-strand breaks.
For research use only. We do not sell to patients.
- Purity : 97.0%
- CAS No.: 92382-74-6
- Formula: C4H10N3NaO2
- Molecular Weight:155.13
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Storage:
-20°C, sealed storage, away from moisture
* The compound is unstable in solutions, freshly prepared is recommended.
Publications Citing Use of MedChemExpress (MCE) DEANO sodium
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Biological Activity
Description
Chemical Information
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CAS No. 92382-74-6
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Appearance Solid
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Molecular Weight 155.13
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Formula C4H10N3NaO2
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Color White to light yellow
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SMILES
CCN(CC)/[N+]([O-])=N/O[Na]
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Synonyms
Diethylamine NONOate sodium; Diethylamine nitric oxide sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* The compound is unstable in solutions, freshly prepared is recommended.
Publications (1)
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Journal Impact Factor
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Most Recent
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Redox Biol
2025 Jun:83:103629. PMID: 40228336
Solvent & Solubility
In Vitro:
H2O : 10 mg/mL (64.46 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Ferroptosis Solutions
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death characterized by lethal lipid peroxidation and sensitivity to suppression by iron chelators or lipophilic radical-trapping antioxidants. The core pathway links cystine uptake through system Xc−, glutathione availability, GPX4-dependent detoxification of phospholipid hydroperoxides, iron-dependent oxidative reactions, and polyunsaturated-phospholipid metabolism into a cell-death program that is biochemically and morphologically distinct from apoptosis, necrosis, and autophagy. The ferroptosis pathway is experimentally linked to phenotype through chemical and genetic perturbation. Erastin induces ferroptosis by inhibiting cystine uptake through system Xc− and weakening antioxidant defenses, while GPX4 inhibition or depletion causes lipid peroxide accumulation and ferroptotic cancer-cell death. ACSL4 and oxidizable arachidonoyl- or adrenoyl-containing phosphatidylethanolamines shape ferroptosis sensitivity by con
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.4462 mL | 32.2310 mL | 64.4621 mL | 161.1552 mL |
| 5 mM | 1.2892 mL | 6.4462 mL | 12.8924 mL | 32.2310 mL | |
| 10 mM | 0.6446 mL | 3.2231 mL | 6.4462 mL | 16.1155 mL | |
| 15 mM | 0.4297 mL | 2.1487 mL | 4.2975 mL | 10.7437 mL | |
| 20 mM | 0.3223 mL | 1.6116 mL | 3.2231 mL | 8.0578 mL | |
| 25 mM | 0.2578 mL | 1.2892 mL | 2.5785 mL | 6.4462 mL | |
| 30 mM | 0.2149 mL | 1.0744 mL | 2.1487 mL | 5.3718 mL | |
| 40 mM | 0.1612 mL | 0.8058 mL | 1.6116 mL | 4.0289 mL | |
| 50 mM | 0.1289 mL | 0.6446 mL | 1.2892 mL | 3.2231 mL | |
| 60 mM | 0.1074 mL | 0.5372 mL | 1.0744 mL | 2.6859 mL |