Dehydroepiandrosterone-d₆

Cat. No.: HY-141901S Purity: 99.5%: Data Sheet
COA

SDS
Handling Instructions
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Dehydroepiandrosterone-d₆ is the deuterium labeled Dehydroepiandrosterone.

For research use only. We do not sell to patients.

Dehydroepiandrosterone-d₆ Chemical Structure

CAS No. : 1261254-39-0

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Other Forms of Dehydroepiandrosterone-d₆:

DHEA In-stock
DHEA (Standard) In-stock
DHEA-d₅ Get quote
Dehydroepiandrosterone-¹³C₃ Get quote

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Biological Activity
Purity & Documentation
References
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Description

Dehydroepiandrosterone-d₆ is the deuterium labeled Dehydroepiandrosterone^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

294.46

Formula

C₁₉H₂₂D₆O₂

CAS No.

1261254-39-0

Unlabeled CAS

53-43-0

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](CC([2H])=C1C([2H])([2H])[C@@](C([2H])([2H])C2)([2H])O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (169.80 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3960 mL	16.9802 mL	33.9605 mL
5 mM	0.6792 mL	3.3960 mL	6.7921 mL
10 mM	0.3396 mL	1.6980 mL	3.3960 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.9%

Select Batch:

Data Sheet (276 KB) SDS (419 KB)

COA (256 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3960 mL	16.9802 mL	33.9605 mL	84.9012 mL
	5 mM	0.6792 mL	3.3960 mL	6.7921 mL	16.9802 mL
	10 mM	0.3396 mL	1.6980 mL	3.3960 mL	8.4901 mL
	15 mM	0.2264 mL	1.1320 mL	2.2640 mL	5.6601 mL
	20 mM	0.1698 mL	0.8490 mL	1.6980 mL	4.2451 mL
	25 mM	0.1358 mL	0.6792 mL	1.3584 mL	3.3960 mL
	30 mM	0.1132 mL	0.5660 mL	1.1320 mL	2.8300 mL
	40 mM	0.0849 mL	0.4245 mL	0.8490 mL	2.1225 mL
	50 mM	0.0679 mL	0.3396 mL	0.6792 mL	1.6980 mL
	60 mM	0.0566 mL	0.2830 mL	0.5660 mL	1.4150 mL
	80 mM	0.0425 mL	0.2123 mL	0.4245 mL	1.0613 mL
	100 mM	0.0340 mL	0.1698 mL	0.3396 mL	0.8490 mL