Deiodoamiodarone
Based on 1 Customer Validation
Deiodoamiodarone (L 3937; Dideiodo Amiodarone) is an intermediate of amiodarone. Amiodarone is a potent calmodulin antagonist.
For research use only. We do not sell to patients.
- Purity: 96.0%
- CAS No.: 23551-25-9
- Formula: C25H31NO3
- Molecular Weight:393.52
-
Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
33 nM
Compound: 3, ddI-Ami
|
Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level
Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level
|
[PMID: 18752950] |
| HL-60 | IC50 |
2.77 μM
Compound: 33m
|
Antiproliferative activity against human HL-60 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human HL-60 cells measured after 24 hrs by MTT assay
|
[PMID: 34605238] |
| MCF7 | IC50 |
5.26 μM
Compound: 33m
|
Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay
|
[PMID: 34605238] |
| MDA-MB-231 | IC50 |
19.4 μM
Compound: 33m
|
Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay
|
[PMID: 34605238] |
| U-937 | IC50 |
3.47 μM
Compound: 33m
|
Antiproliferative activity against human U-937 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human U-937 cells measured after 24 hrs by MTT assay
|
[PMID: 34605238] |
Chemical Information
-
CAS No. 23551-25-9
-
Appearance Liquid (Density: 1.08 g/cm3)
-
Molecular Weight 393.52
-
Formula C25H31NO3
-
Color Light yellow to yellow
-
SMILES
O=C(C1=CC=C(C=C1)OCCN(CC)CC)C2=C(OC3=CC=CC=C23)CCCC
-
Synonyms
L 3937; Dideiodo Amiodarone
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (254.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5412 mL | 12.7058 mL | 25.4117 mL | 63.5292 mL |
| 5 mM | 0.5082 mL | 2.5412 mL | 5.0823 mL | 12.7058 mL | |
| 10 mM | 0.2541 mL | 1.2706 mL | 2.5412 mL | 6.3529 mL | |
| 15 mM | 0.1694 mL | 0.8471 mL | 1.6941 mL | 4.2353 mL | |
| 20 mM | 0.1271 mL | 0.6353 mL | 1.2706 mL | 3.1765 mL | |
| 25 mM | 0.1016 mL | 0.5082 mL | 1.0165 mL | 2.5412 mL | |
| 30 mM | 0.0847 mL | 0.4235 mL | 0.8471 mL | 2.1176 mL | |
| 40 mM | 0.0635 mL | 0.3176 mL | 0.6353 mL | 1.5882 mL | |
| 50 mM | 0.0508 mL | 0.2541 mL | 0.5082 mL | 1.2706 mL | |
| 60 mM | 0.0424 mL | 0.2118 mL | 0.4235 mL | 1.0588 mL | |
| 80 mM | 0.0318 mL | 0.1588 mL | 0.3176 mL | 0.7941 mL | |
| 100 mM | 0.0254 mL | 0.1271 mL | 0.2541 mL | 0.6353 mL |
Deiodoamiodarone Related Classifications
HY-114928 Related Classifications
Powered by Bioz