Desethylene Ciprofloxacin hydrochloride
Based on 1 Customer Validation
Desethylene Ciprofloxacin hydrochloride is a major metabolite and degradation product of Ciprofloxacin (HY-B0356). Desethylene Ciprofloxacin hydrochloride inhibits topoisomerase (Topoisomerase) IIα and IIβ-mediated DNA relaxation.
For research use only. We do not sell to patients.
- Purity : 98.12%
- CAS No.: 528851-31-2
- Formula: C15H17ClFN3O3
- Molecular Weight:341.77
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-122139R
Desethylene Ciprofloxacin hydrochloride (Standard)Reference Standard -
HY-B0268S1
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HY-121884R
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HY-13234S
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HY-W018386A
3-Bromo-L-tyrosine TFAAmino Acid Derivative
All Topoisomerase Isoforms
More
Biological Activity
Description
In Vitro
Desethylene Ciprofloxacin (10-300 μM; 15 min) inhibits human topoisomerase IIα and IIβ-mediated DNA relaxation only at high concentrations of 200-300 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 528851-31-2
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Appearance Solid
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Molecular Weight 341.77
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Formula C15H17ClFN3O3
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Color White to off-white
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SMILES
FC1=CC2=C(N(C=C(C2=O)C(O)=O)C3CC3)C=C1NCCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 4.17 mg/mL (12.20 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9259 mL | 14.6297 mL | 29.2594 mL | 73.1486 mL |
| 5 mM | 0.5852 mL | 2.9259 mL | 5.8519 mL | 14.6297 mL | |
| 10 mM | 0.2926 mL | 1.4630 mL | 2.9259 mL | 7.3149 mL |
Desethylene Ciprofloxacin hydrochloride Related Classifications
HY-122139 Related Classifications
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