Dextran T1 (MW 1,000)
Based on 1 Customer Validation
Dextran T1 (Dextran 1; Dextran D1) (with a molecular weight of 1,000) is a dehydrated glucose polymer with an average molecular weight of 1,000. Dextran T1 (MW 1,000) has excellent biodegradability and biocompatibility, and can be used as a nanobody carrier scaffold and a freeze-drying protectant. Dextran T1 (MW 1,000) promotes the retention of circulating tumor cells in the capillary bed.
For research use only. We do not sell to patients.
- CAS No.: 9004-54-0
- Formula: (C6H10O5)n
- Molecular Weight:800-1200
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Dextran T60 (MW 60,000)Biochemical Assay Reagent
Biological Activity
Description
In Vitro
Dextran T1 (MW 1,000) exhibits protective effects during the freeze-drying process of Aviscumine (a recombinant protein). At a concentration of 8%, it can form a completely amorphous freeze-dried cake, thereby avoiding the damage to the protein caused by the phase separation of crystals[1].
Dextran T1 (MW 1,000) can be used as a scaffold to construct a nanobody-drug conjugate (NBBC-Dex1-PS). The NBBC-Dex1-PS can penetrate into the interior of the tumor sphere, and its penetration behavior is similar to that of the conjugates using larger molecular weight Dextran (5k, 10k)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-54-0
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Appearance Solid
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Molecular Weight 800-1200
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Formula (C6H10O5)n
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Color White to off-white
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SMILES
[Dextran T1 (MW 1,000)]
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Synonyms
Dextran 1; Dextran D1; Dextran T1(MW 800-1200)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Gloger O, et al. Lyoprotection of aviscumine with low molecular weight dextrans. Int J Pharm. 2003 Jul 9;260(1):59-68. [Content Brief]
[2]. Bitsch P, et al. Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids. Pharmaceutics. 2023 Sep 22;15(10):2374. [Content Brief]
[3]. Skolnik G, et al. The influence of trauma, Dextran 1000, and Dextran 40 on the lodgement of circulating tumor cells. J Cancer Res Clin Oncol. 1980;97(3):241-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dextran T1 (MW 1,000) Related Classifications
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