DFP-11207
DFP-11207 is an orally active fluoropyrimidine cytotoxic agent. DFP-11207 combines a 5-FU (HY-90006) pro-drug with a reversible DPD inhibitor and a potent inhibitor of OPRT, resulting in enhanced pharmacological activity of 5-FU with decreased gastrointestinal and myelosuppressive toxicities. DFP-11207 can be used for the research of cancer .
For research use only. We do not sell to patients.
- CAS No.: 1296177-16-6
- Formula: C32H26ClFN4O12
- Molecular Weight:713.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1296177-16-6
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Molecular Weight 713.02
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Formula C32H26ClFN4O12
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SMILES
O=C(C1=CC(OC(CC)=O)=NC(OC(CC)=O)=C1)OC2=CC(OC(C3=CC=CC(C(N(C(N(COCC)C=C4F)=O)C4=O)=O)=C3)=O)=NC=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)