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Cat. No.: HY-105969

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Dichloromethotrexate

(Synonyms: NSC-29630; 3',5'-Dichloromethotrexate)

Dichloromethotrexate (NSC-29630), an orally active antitumor agent, shows antitumor effect against L1210 leukemia and C3H lymphosarcoma in mice.

For research use only. We do not sell to patients.

CAS No.: 528-74-5
Formula: C₂₀H₂₀Cl₂N₈O₅
Molecular Weight:523.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Dichloromethotrexate Chemical Structure

CAS No.: 528-74-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Dichloromethotrexate (NSC-29630), an orally active antitumor agent, shows antitumor effect against L1210 leukemia and C3H lymphosarcoma in mice^[1].

Chemical Information

CAS No. 528-74-5
Molecular Weight 523.33
Formula C₂₀H₂₀Cl₂N₈O₅
SMILES

NC1=NC(N)=NC2=NC=C(CN(C3=C(C=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3Cl)Cl)C)N=C12
Synonyms

NSC-29630; 3',5'-Dichloromethotrexate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. FREI E 3rd, et al. CLINICAL STUDIES OF DICHLOROMETHOTREXATE (NSC 29630). Clin Pharmacol Ther. 1965 Mar-Apr;6:160-71. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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