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Cat. No.: HY-132181

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Dimethylamiloride hydrochloride

3 Cited Publications

Customer Review

Based on 3 publication(s) in Google Scholar

Dimethylamiloride hydrochloride is a Na⁺/H⁺ exchanger NHE inhibitor with K_i values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research.

For research use only. We do not sell to patients.

CAS No.: 2235-97-4
Formula: C₈H₁₃Cl₂N₇O
Molecular Weight:294.14

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Dimethylamiloride hydrochloride Chemical Structure

CAS No.: 2235-97-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 2235-97-4
Molecular Weight 294.14
Formula C₈H₁₃Cl₂N₇O
SMILES

O=C(C1=NC(Cl)=C(N(C)C)N=C1N)NC(N)=N.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Cell Metab

Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression. [Abstract]

2025 Sep 24:S1550-4131(25)00385-7. PMID: 40997802
J Dermatolog Treat

Engineering extracellular vesicles with macrophage membrane fusion for ameliorating imiquimod-induced psoriatic skin inflammation. [Abstract]

2023 Dec;34(1):2220445. PMID: 38073229
Electrophoresis

Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε-Aminocaproic Acid and Triethylenetetramine. [Abstract]

2025 Sep 23. PMID: 40988426

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Masereel B, et al. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem. 2003 Jun;38(6):547-54. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Dimethylamiloride hydrochloride

3 Cited Publications

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Dimethylamiloride hydrochloride

5-(N,N-Hexamethylene)-amiloride

BI-9627 hydrochloride

Zoniporide hydrochloride hydrate

NHE3-IN-2

FR183998 free base

NHE3-IN-1

Eniporide

Cariporide

Tenapanor

Zoniporide

Tenapanor hydrochloride

Rimeporide

Publications Citing Use of MedChemExpress (MCE) Dimethylamiloride hydrochloride

Biological Activity

Chemical Information

Publications (3)

Purity & Documentation

References

Calculators

Help & FAQs

Dimethylamiloride hydrochloride

5-(N,N-Hexamethylene)-amiloride

BI-9627 hydrochloride

Zoniporide hydrochloride hydrate

NHE3-IN-2

FR183998 free base

NHE3-IN-1

Eniporide

Cariporide

Tenapanor

Zoniporide

Tenapanor hydrochloride

Rimeporide

Publications Citing Use of MedChemExpress (MCE) Dimethylamiloride hydrochloride

Biological Activity

Chemical Information

Publications (3)

Purity & Documentation

References

Calculators

Help & FAQs

Dimethylamiloride hydrochloride Related Classifications

HY-132181 Related Classifications