1. GPCR/G Protein
    Neuronal Signaling
  2. Sigma Receptor
  3. Ditolylguanidine

Ditolylguanidine (Synonyms: 1,3-Di-o-tolylguanidine; DTG)

Cat. No.: HY-14218 Purity: 99.26%
Handling Instructions

Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).

For research use only. We do not sell to patients.

Ditolylguanidine Chemical Structure

Ditolylguanidine Chemical Structure

CAS No. : 97-39-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
1 g USD 50 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor)[1].

IC50 & Target

Sigma receptor[1]

Clinical Trial
Molecular Weight

239.32

Formula

C₁₅H₁₇N₃

CAS No.

97-39-2

SMILES

CC1=C(NC(NC2=CC=CC=C2C)=N)C=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (626.78 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1785 mL 20.8925 mL 41.7851 mL
5 mM 0.8357 mL 4.1785 mL 8.3570 mL
10 mM 0.4179 mL 2.0893 mL 4.1785 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (10.45 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.45 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Ditolylguanidine
Cat. No.:
HY-14218
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