ITGAV - integrin subunit alpha V Gene

Also Known as CD51; MSK8; VNRA; VTNR

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 3685

About ITGAV

Cytogenetic location: 2q32.1 Genomic coordinates (GRCh38): 2:186,590,056-186,680,901 (from NCBI)

This gene has 23 transcripts (splice variants), 243 orthologues, 17 paralogues and is associated with 73 phenotypes. Ubiquitous expression in thyroid (RPKM 45.9), ovary (RPKM 36.3) and 24 other tissues.

Summary

The product of this gene belongs to the Integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the Vitronectin receptor. This Integrin may regulate angiogenesis and Cancer progression. Alternative splicing results in multiple transcript variants. Note that the Integrin alpha 5 and Integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

ITGAV Products (3)

mRNA	Protein	Name
NM_001144999.3	NP_001138471.2	integrin alpha-V isoform 2 precursor
NM_001145000.3	NP_001138472.2	integrin alpha-V isoform 3 precursor
NM_002210.5	NP_002201.2	integrin alpha-V isoform 1 preproprotein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
contributes to C-X3-C chemokine binding	IDA IDA: Inferred from direct assay	23125415	GOA
enables extracellular matrix binding	IDA IDA: Inferred from direct assay	22505472	GOA
enables extracellular matrix protein binding	IDA IDA: Inferred from direct assay	7525578	GOA
contributes to fibroblast growth factor binding	IDA IDA: Inferred from direct assay	18441324	GOA
enables fibronectin binding	IDA IDA: Inferred from direct assay	24658351	GOA
contributes to insulin-like growth factor I binding	IDA IDA: Inferred from direct assay	19578119	GOA
enables integrin binding	IPI IPI: Inferred from physical interaction	20826760	GOA
contributes to neuregulin binding	IDA IDA: Inferred from direct assay	20682778	GOA
enables protease binding	IDA IDA: Inferred from direct assay	22505472	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	1694173	GOA
enables voltage-gated calcium channel activity	IDA IDA: Inferred from direct assay	18395422	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in angiogenesis	IEP IEP: Inferred from expression pattern	11866539	GOA
involved in apolipoprotein A-I-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	23726972	GOA
involved in apoptotic cell clearance	IGI IGI: Inferred from genetic interaction	20826760	GOA
involved in calcium ion transmembrane transport	IDA IDA: Inferred from direct assay	18395422	GOA
involved in cell adhesion	IDA IDA: Inferred from direct assay	10218736	GOA
involved in cell adhesion mediated by integrin	IDA IDA: Inferred from direct assay	12807887	GOA
involved in cell migration	IMP IMP: Inferred from mutant phenotype	26934001	GOA
involved in cell-matrix adhesion	IMP IMP: Inferred from mutant phenotype	7525578	GOA
involved in cell-substrate adhesion	IMP IMP: Inferred from mutant phenotype	19933311	GOA
involved in endodermal cell differentiation	IMP IMP: Inferred from mutant phenotype	23154389	GOA
involved in heterotypic cell-cell adhesion	IMP IMP: Inferred from mutant phenotype	20563599	GOA
involved in integrin-mediated signaling pathway	IDA IDA: Inferred from direct assay	11970960	GOA
involved in integrin-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	26934001	GOA
involved in negative chemotaxis	IMP IMP: Inferred from mutant phenotype	23726972	GOA
involved in negative regulation of entry of bacterium into host cell	IDA IDA: Inferred from direct assay	10570297	GOA
involved in negative regulation of extrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	10708943	GOA
involved in negative regulation of lipid storage	IMP IMP: Inferred from mutant phenotype	15215180	GOA
involved in negative regulation of lipid transport	IMP IMP: Inferred from mutant phenotype	15215180	GOA
involved in negative regulation of lipoprotein metabolic process	IMP IMP: Inferred from mutant phenotype	15215180	GOA
acts upstream of or within negative regulation of low-density lipoprotein receptor activity	IMP IMP: Inferred from mutant phenotype	15215180	GOA
involved in negative regulation of macrophage derived foam cell differentiation	IMP IMP: Inferred from mutant phenotype	15215180	GOA
involved in positive regulation of cell adhesion	IDA IDA: Inferred from direct assay	10708943	GOA
involved in positive regulation of cell population proliferation	IDA IDA: Inferred from direct assay	19578119	GOA
involved in positive regulation of intracellular signal transduction	IMP IMP: Inferred from mutant phenotype	26934001	GOA
involved in positive regulation of small GTPase mediated signal transduction	IMP IMP: Inferred from mutant phenotype	26934001	GOA
involved in regulation of phagocytosis	IDA IDA: Inferred from direct assay	10570297	GOA
involved in substrate adhesion-dependent cell spreading	IDA IDA: Inferred from direct assay	24658351	GOA
involved in symbiont entry into host cell	IMP IMP: Inferred from mutant phenotype	25063885	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of alphav-beta3 integrin-HMGB1 complex	IDA IDA: Inferred from direct assay	20826760	GOA
part of alphav-beta3 integrin-IGF-1-IGF1R complex	IDA IDA: Inferred from direct assay	19578119	GOA
located in cell surface	IDA IDA: Inferred from direct assay	1918072	GOA
located in filopodium membrane	IDA IDA: Inferred from direct assay	25063885	GOA
located in focal adhesion	IDA IDA: Inferred from direct assay	17158881	GOA
part of integrin alphav-beta1 complex	IPI IPI: Inferred from physical interaction	25398877	GOA
part of integrin alphav-beta3 complex	IDA IDA: Inferred from direct assay	20826760	GOA
part of integrin alphav-beta3 complex	IPI IPI: Inferred from physical interaction	11546839	GOA
part of integrin alphav-beta5 complex	IDA IDA: Inferred from direct assay	25063885	GOA
part of integrin alphav-beta5 complex	IPI IPI: Inferred from physical interaction	1694173	GOA
part of integrin alphav-beta6 complex	IDA IDA: Inferred from direct assay	22278742	GOA
part of integrin alphav-beta6 complex	IPI IPI: Inferred from physical interaction	25383667	GOA
part of integrin alphav-beta8 complex	IDA IDA: Inferred from direct assay	1918072	GOA
part of integrin alphav-beta8 complex	IPI IPI: Inferred from physical interaction	30061598	GOA
part of integrin complex	IDA IDA: Inferred from direct assay	15215180	GOA
located in lamellipodium membrane	IDA IDA: Inferred from direct assay	25063885	GOA
located in microvillus membrane	IDA IDA: Inferred from direct assay	25063885	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	21310825	GOA
located in ruffle membrane	IDA IDA: Inferred from direct assay	25063885	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ITGAV Protein Structure

FG-GAP

Integrin_alpha2

Integrin_alpha

0
200
400
600
800
1000
1048 a.a.

Protein Preferred Names	Protein Names
integrin alpha-V	antigen identified by monoclonal antibody L230

ITGAV Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ITGAV	P06756	ITGB5	Homo sapiens	P18084	Chromatography	1694173
Intra	ITGAV	P06756	ITGB5	Homo sapiens	P18084	Solid Phase Assay	1694173
Intra	ITGAV	P06756	ITGB6	Homo sapiens	P18564	GMS	21677751
Intra	ITGAV	P06756	ITGB6	Homo sapiens	P18564	GMS	25383667
Intra	ITGAV	P06756	ITGB6	Homo sapiens	P18564	EM	28534487
Intra	ITGAV	P06756	ITGB6	Homo sapiens	P18564	TEM	21677751
Intra	ITGAV	P06756	ITGB6	Homo sapiens	P18564	X-Ray Diffraction	25383667
Intra	ITGAV	P06756	ITGB6	Homo sapiens	P18564	Ion Exchange Chrom	25383667
Intra	ITGAV	P06756	ITGB3	Homo sapiens	P05106	Anti Bait CoIP	20639902
Intra	ITGAV	P06756	ITGB3	Homo sapiens	P05106	X-Ray Diffraction	15299032
Intra	ITGAV	P06756	ITGB3	Homo sapiens	P05106	ELISA	16099422
Intra	ITGAV	P06756	ITGB3	Homo sapiens	P05106	X-Ray Diffraction	11546839
Intra	ITGAV	P06756	ITGB3	Homo sapiens	P05106	Solid Phase Assay	1694173
Intra	ITGAV	P06756	ITGB3	Homo sapiens	P05106	GMS	24658351

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ITGAV Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72535	Integrin alpha V beta 8 Protein, Human (HEK293, His)	P06756-1 (F31-V992)&P26012-1 (E43-R684)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73865	Integrin alpha V beta 8 Protein, Human (HEK293, His, solution)	P06756-1 (F31-V992)&P26012-1 (E43-R684)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73867	Integrin alpha V beta 6 Protein, Human (HEK293, Flag-His)	P06756-1 (F31-V992)&P18564-1 (G22-N707)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73868	Integrin alpha V beta 3 Protein, Human (HEK293, His, solution)	P06756-1 (F31-V992)&P05106-1 (G27-D718)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P77719	Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi)	P06756-1 (F31-V992)&P05106-1 (G27-D718)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77720	Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi)	P06756-1 (F31-V992)&P18084 (G24-N719)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77721	Integrin alpha V beta 6 Protein, Human (HEK293, His-Avi)	P06756-1 (F31-V992)&P18564-1 (G22-N707)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P77722	Integrin alpha V beta 8 Protein, Human (HEK293, His-Avi)	P06756-1 (F31-V992)&P26012-1 (E43-R684)	≥ 95%, as determined by Bis-Tris PAGE.

ITGAV Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80417	Integrin alpha V Antibody (YA338)	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

Related Diseases

Diseases	Alias
West Nile Virus	West Nile Virus, Susceptibility To Wnv Wnv, Susceptibility To West Nile Viral Infection Encephalitis, West Nile Fever West Nile Fever
Herpes Simplex	Herpes Simplex Infections Herpesvirus Hominis Disease Herpes Simplex Disease Herpesviral Infection Due To Herpes Simplex Infections Due To Simplex Virus Herpes Nos
Priapism	Mentulagra Priapism, Familial Idiopathic Familial Idiopathic Priapism Pathologic Erection Painful Erection
Insulin-Like Growth Factor I	Insulin-Like Growth Factor I Deficiency IGF1 DEFICIENCY Insulin-Like Growth Factor I, Resistance To Growth Retardation With Deafness And Mental Retardation Due To Igf1 Deficiency Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency Growth Delay Due To Insulin-Like Growth Factor I Resistance IGF1RES Igf-I Resistance Somatomedin, End-Organ Insensitivity To Somatomedin-C Somatomedin-C, Resistance To Growth Retardation With Sensorineural Deafness And Mental Retardation Insulin-Like Growth Factor 1 Resistance To Igf-1 Resistance Somatomedin End-Organ Insensitivity To Somatomedin-C Resistance To Growth Restriction With Sensorineural Deafness And Intellectual Disability Growth Delay-Deafness-Intellectual Disability Syndrome Growth Delay-Hearing Loss-Intellectual Disability Syndrome Igf-1 Deficiency Primary Insulin-Like Growth Factor Deficiency Resistance To Igf-1 Insulin-Like Growth Factor 1 Resistance End-Organ Insensitivity To Somatomedin Igf1 Resistance Resistance To Insulin-Like Growth Factor I Resistance To Somatomedin-C Insulin-Like Growth Factor 1, Resistance To
Pharyngoconjunctival Fever	Pharyngo-Conjunctival Fever Adenoviral Pharyngoconjunctivitis Adenovirus Infections, Human
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Mouth Disease	Mouth Diseases Mouth Disorders
Sarcoma	Connective And Soft Tissue Neoplasm Tumor Of Soft Tissue And Skeleton Sarcomas Sarcoma - Category
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Kaposi Sarcoma	Kaposi'S Sarcoma Kaposi Sarcoma, Susceptibility To Kaposi'S Sarcoma Of Lung Kaposi'S Sarcoma Of Palate Kaposi'S Sarcoma Of Soft Tissue Kaposi'S Sarcoma-Associated Herpesvirus Multiple Idiopathic Pigmented Hemangiosarcoma Multiple Idiopathic Pigmented Hemangiosarcoma, Susceptibility To African Lymphadenopathic Kaposi'S Sarcoma Anal Kaposi'S Sarcoma Cardiac Kaposi'S Sarcoma Central Nervous System Kaposi'S Sarcoma Conjunctival Kaposi'S Sarcoma Corneal Kaposi'S Sarcoma Cutaneous Kaposi'S Sarcoma Esophageal Kaposi'S Sarcoma Gallbladder Kaposi'S Sarcoma Gastric Kaposi'S Sarcoma Intestinal Kaposi'S Sarcoma Kaposi'S Sarcoma Of Anus Kaposi'S Sarcoma Of Central Nervous System Kaposi'S Sarcoma Of Conjunctiva Kaposi'S Sarcoma Of Cornea Kaposi'S Sarcoma Of Esophagus Kaposi'S Sarcoma Of Gastrointestinal Sites Kaposi'S Sarcoma Of Heart Kaposi'S Sarcoma Of Lymph Nodes Kaposi'S Sarcoma Of Penis Kaposi'S Sarcoma Of Skin Kaposi'S Sarcoma Of Soft Tissues Kaposi'S Sarcoma Of The Cns Kaposi'S Sarcoma Of The Gallbladder Kaposi'S Sarcoma Of The Prostate Kaposi'S Sarcoma, Lung Kaposi'S Sarcoma, Skin Lymph Node Kaposi'S Sarcoma Lymphadenopathic Kaposi'S Sarcoma Palate Kaposi'S Sarcoma Penis Kaposi'S Sarcoma Prostate Kaposi'S Sarcoma Pulmonary Kaposi'S Sarcoma Soft Tissue Kaposi'S Sarcoma Hhv8 Human Herpesvirus 8 Kshv Kaposi Sarcoma Herpesvirus Mediterranean Kaposi Sarcoma Non Aids Related Kaposi Sarcoma Sarcoma, Kaposi Sarcoma, Kaposi, Susceptibility To Non-Aids-Related Kaposi Sarcoma Angiolymphoid Hyperplasia Angiofollicular Ganglionic Hyperplasia Multi-Centric Castleman'S Disease
Bone Giant Cell Tumor	Giant Cell Tumor Of Bone Osteoclastoma Gct Of Bone Bone Giant Cell Tumour Giant Cell Myeloma Giant Cell Neoplasm Of Bone Giant Cell Tumour Of Bone
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Pigmented Villonodular Synovitis	Diffuse Giant Cell Tumor Of Tenosynovium Villous Tenosynovitis Diffuse Pigmented Villonodular Synovitis Diffuse-Type Gct Diffuse-Type Giant Cell Tumor Localized Pigmented Villonodular Synovitis Tgct Tsgct Tenosynovial Giant Cell Tumor Tenosynovial Giant Cell Tumors Synovitis Pigmented Villonodular Synovitis, Pigmented Villonodular Fibrous Histiocytoma Of Tendon Sheath Testicular Germ Cell Tumor Chronic Haemorrhagic Villous Synovitis Pvns - [Pigmented Villonodular Synovitis] Villonodular Synovitis
Arrhythmogenic Right Ventricular Cardiomyopathy	Arrhythmogenic Right Ventricular Dysplasia Arvc Arvd Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Arvc Cardiomyopathy Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia Arvd/C Right Ventricular Dysplasia, Arrhythmogenic Ventricular Dysplasia, Right, Arrhythmogenic Cardiomyopathy, Ventricular, Right, Arrhythmogenic Dysplasia, Arrhythmogenic Right Ventricular
Glanzmann Thrombasthenia 1	Glanzmann Thrombasthenia Thrombasthenia Of Glanzmann And Naegeli Glanzmann'S Thrombasthenia Bdplt2 Platelet Glycoprotein Iib-Iiia Deficiency Deficiency Of Platelet Fibrinogen Receptor GT1 Gt Platelet Fibrinogen Receptor Deficiency Glycoprotein Complex Iib-Iiia Deficiency Deficiency Of Glycoprotein Complex Iib-Iiia Glycoprotein Iib/Iiia Defect Glanzmann Thrombasthenia, Type A Thrombasthenia Bleeding Disorder, Platelet-Type, 2 Gp Iib-Iiia Complex Deficiency Deficiency Of Gp Iib-Iiia Complex Platelet-Type Bleeding Disorder 2 Thrombocytasthenia Deficiency Of Gp 2b 3a Complex Diacyclothrombopathia 2b 3a Glanzmann Thrombasthenia Type A Platelet Fibrinogen Receptor, Deficiency Of Platelet Glycoprotein 2b 3a Deficiency Glanzmann Disease Glanzmann-Naegeli Disorder Hereditary Hemorrhagic Thrombasthenia Hereditary Thrombasthenia Bleeding Disorder Platelet-Type 2
Bone Benign Neoplasm
Focal Segmental Glomerulosclerosis	Familial Idiopathic Steroid-Resistant Nephrotic Syndrome Focal Glomerulosclerosis Fsgs Segmental Glomerulosclerosis Glomerulosclerosis, Focal Segmental Fgs Focal Glomerular Sclerosis Familial Idiopathic Nephrotic Syndrome Focal Sclerosis With Hyalinosis Glomerulosclerosis, Focal Glomerulosclerosis Focal Glomerulosclerosis, Segmental, Focal Focal Segmental Glomerulosclerosis, Not Otherwise Specified
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Intrahepatic Bile Duct Adenoma	Adenoma Of Intrahepatic Bile Duct Adenoma Of The Intrahepatic Bile Duct

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06961	ITGAV Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS16754	Itgav Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23193	Itgav Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990667B	STX-100 (Biotinylated)	Inhibitor	≥99.0%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ITGAV	VGNC	VGNC:67849
Mus musculus	ITGAV	MGD	MGI:96608
Rattus norvegicus	ITGAV	RGD	RGD:1310613
Canis familiaris	ITGAV	VGNC	VGNC:42134
Macaca mulatta	ITGAV	VGNC	VGNC:73783
Bos taurus	ITGAV	VGNC	VGNC:30323
Others	ITGAV	NCBI