AIDA - axin interactor, dorsalization associated Gene

Also Known as C1orf80

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64853

About AIDA

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:222,668,013-222,712,491 (from NCBI)

This gene has 6 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in fat (RPKM 42.6), testis (RPKM 31.5) and 25 other tissues.

Summary

Predicted to enable phosphatidylinositol binding activity. Acts upstream of or within negative regulation of JUN kinase activity. Predicted to be located in cytoplasm. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

AIDA Products (1)

mRNA Protein Name
NM_022831.4 NP_073742.2 axin interactor, dorsalization-associated protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21900206 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of JUN kinase activity IDA
IDA: Inferred from direct assay
17681137 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AIDA Protein Structure

Aida_N

Aida_N: Aida N-terminus (9 - 113)

Aida_C2

Aida_C2: Cytoskeletal adhesion (155 - 301)

  • 0
  • 100
  • 200
  • 306 a.a.
Protein Preferred Names Protein Names

axin interactor, dorsalization-associated protein

  • axin interaction partner and dorsalization antagonist

AIDA Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
AIDA Q96BJ3 DDX41 Homo sapiens Q9UJV9
Validated Y2H
32296183
Intra
AIDA Q96BJ3 DDX41 Homo sapiens Q9UJV9
Y2H Array
32296183
Intra
AIDA Q96BJ3 DDX41 Homo sapiens Q9UJV9
Y2H Prey Pooling
32296183
Intra
AIDA Q96BJ3 RPL36A Homo sapiens P83881
Y2H Prey Pooling
32296183
Intra
AIDA Q96BJ3 RPL36A Homo sapiens P83881
Y2H Array
32296183
Intra
AIDA Q96BJ3 EMSY Homo sapiens Q7Z589-5
Y2H Array
32296183
Intra
AIDA Q96BJ3 EMSY Homo sapiens Q7Z589-5
Y2H Prey Pooling
32296183
Intra
AIDA Q96BJ3 PINX1 Homo sapiens Q96BK5
Y2H Prey Pooling
32296183
Intra
AIDA Q96BJ3 PINX1 Homo sapiens Q96BK5
Validated Y2H
32296183
Intra
AIDA Q96BJ3 PINX1 Homo sapiens Q96BK5
Y2H Array
32296183
Intra
AIDA Q96BJ3 PINX1 Homo sapiens Q96BK5
Y2H
21900206
Intra
AIDA Q96BJ3 LNX1 Homo sapiens Q8TBB1
Y2H Prey Pooling
25416956
Intra
AIDA Q96BJ3 LNX1 Homo sapiens Q8TBB1
Validated Y2H
25416956
Intra
AIDA Q96BJ3 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
AIDA Q96BJ3 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
AIDA Q96BJ3 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
AIDA Q96BJ3 FAM118A Homo sapiens Q9NWS6
Y2H Array
32296183
Intra
AIDA Q96BJ3 FAM118A Homo sapiens Q9NWS6
Y2H Prey Pooling
32296183
Intra
AIDA Q96BJ3 FAM118A Homo sapiens Q9NWS6
Y2H Prey Pooling
25416956
Intra
AIDA Q96BJ3 FAM118A Homo sapiens Q9NWS6
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-101311 UPF-523 Antagonist 99.89% Phase 4

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00489 AIDA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00736 ANKS1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18335 Aida Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24814 Aida Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus AIDA MGD MGI:1919737
Macaca mulatta AIDA VGNC VGNC:99840
Canis familiaris AIDA VGNC VGNC:37734
Rattus norvegicus AIDA RGD RGD:1592746
Bos taurus AIDA VGNC VGNC:25758
Felis catus AIDA VGNC VGNC:59699
Others AIDA NCBI