IP6K2-IN-1
Based on 1 Customer Validation
IP6K2-IN-1 is a selective flavonoid-based IP6K2 inhibitor with an IC50 value of 0.55 μM. IP6K2-IN-1 shows higher inhibitory potency against IP6K2 than IP6K1 and IP6K3. IP6K2-IN-1 can be utilised as a hit compound for further structural modifications of IP6K2 inhibitors.
For research use only. We do not sell to patients.
- Purity : 99.47%
- CAS No.: 2926679-10-7
- Formula: C16H10O7
- Molecular Weight:314.25
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IP6K2 |
In Vitro
IP6K2-IN-1 (Compound 20s) shows IC50 value of 2.87 µM against IP6K1 resulting 5.22-fold IC50 ratio of IP6K1/IP6K2 and IC50 value of 3.56 µM against IP6K3, resulting 6.47-fold IC50 ratio of IP6K3/IP6K2[1].
IP6K2-IN-1 failed to reduce IP7 levels in HCT116 cells, indicating low cell permeability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2926679-10-7
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Appearance Solid
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Molecular Weight 314.25
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Formula C16H10O7
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Color Yellow to brown
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SMILES
OC1=C(O)C=C(C(C(O)=C(C2=CC(C(O)=O)=CC=C2)O3)=O)C3=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IP6K2-IN-1 Related Classifications
HY-161032 Related Classifications
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