Temuterkib (Standard)

(Synonyms: LY3214996 (Standard))

Temuterkib (Standard) is the analytical standard of Temuterkib (HY-101494). This product is intended for research and analytical applications. Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.

For research use only. We do not sell to patients.

  • CAS No.: 1951483-29-6
  • Formula: C22H27N7O2S
  • Molecular Weight:453.56
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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