2. DKI5

DKI5, also known as (E)-N’-benzylidenehydrazinecarbothiohydrazide, is a LOX-1 inhibitor with an IC50 value of 22.5 μM.

For research use only. We do not sell to patients.

DKI5 Chemical Structure

DKI5 Chemical Structure

CAS No. : 1101130-96-4

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5 mg USD 110 In-stock
10 mg USD 175 In-stock
25 mg USD 320 In-stock
50 mg USD 500 In-stock
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Based on 1 publication(s) in Google Scholar

DKI5 Related Antibodies

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Description

DKI5, also known as (E)-N’-benzylidenehydrazinecarbothiohydrazide, is a LOX-1 inhibitor with an IC50 value of 22.5 μM[1].

Molecular Weight

194.26

Formula

C8H10N4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NNC(N/N=C/C1=CC=CC=C1)=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (257.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.1477 mL 25.7387 mL 51.4774 mL
5 mM 1.0295 mL 5.1477 mL 10.2955 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.1477 mL 25.7387 mL 51.4774 mL 128.6935 mL
5 mM 1.0295 mL 5.1477 mL 10.2955 mL 25.7387 mL
10 mM 0.5148 mL 2.5739 mL 5.1477 mL 12.8694 mL
15 mM 0.3432 mL 1.7159 mL 3.4318 mL 8.5796 mL
20 mM 0.2574 mL 1.2869 mL 2.5739 mL 6.4347 mL
25 mM 0.2059 mL 1.0295 mL 2.0591 mL 5.1477 mL
30 mM 0.1716 mL 0.8580 mL 1.7159 mL 4.2898 mL
40 mM 0.1287 mL 0.6435 mL 1.2869 mL 3.2173 mL
50 mM 0.1030 mL 0.5148 mL 1.0295 mL 2.5739 mL
60 mM 0.0858 mL 0.4290 mL 0.8580 mL 2.1449 mL
80 mM 0.0643 mL 0.3217 mL 0.6435 mL 1.6087 mL
100 mM 0.0515 mL 0.2574 mL 0.5148 mL 1.2869 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DKI51101130-96-4DKI 5DKI-5Inhibitorinhibitorinhibit

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