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DNA2 inhibitor C5 

Cat. No.: HY-128729
Handling Instructions

DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress.

For research use only. We do not sell to patients.

DNA2 inhibitor C5 Chemical Structure

DNA2 inhibitor C5 Chemical Structure

CAS No. : 35973-25-2

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Description

DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress[1].

IC50 & Target

IC50: 20 μM (DNA2 nuclease)[1]

Molecular Weight

234.17

Formula

C₁₀H₆N₂O₅

CAS No.

35973-25-2

SMILES

O=C(C1=C(O)C2=CC=CC([N+]([O-])=O)=C2N=C1)O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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DNA2 inhibitor C5
Cat. No.:
HY-128729
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