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Cat. No.: HY-172180

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DNMT-IN-4

DNMT-IN-4 (Compound 4d) is a DNMT inhibitor with an IC₅₀ of 5.78 µM. DNMT-IN-4 can induce apoptosis and has anticancer activity.

For research use only. We do not sell to patients.

Formula: C₂₂H₂₅ClN₄S₂
Molecular Weight:445.04

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

DNMT-IN-4 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DNMT-IN-4 (Compound 4d) is a DNMT inhibitor with an IC₅₀ of 5.78 µM. DNMT-IN-4 can induce apoptosis and has anticancer activity^[1].

IC₅₀ & Target

IC50: 5.78? μM (DNMT)^[1].

All DNA Methyltransferase Isoforms :

Chemical Information

Molecular Weight 445.04
Formula C₂₂H₂₅ClN₄S₂
SMILES

ClC(C=CC=C1)=C1C(N2CCC3=C(C2)C=CS3)C(S4)=NN=C4NC5CCCCC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Karakuş, S., et al. Synthesis and Apoptotic Effects of DNMT Inhibition Targeted Novel Hybrid Molecules Bearing Thiadiazole and Clopidogrel for Cancer Treatment. Polycyclic Aromatic Compounds, 1–24.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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DNMT-IN-4

All DNA Methyltransferase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DNMT-IN-4 Related Classifications

HY-172180 Related Classifications