2. Others
  3. Biochemical Assay Reagents
  4. DOPE-mPEG20000

DOPE-mPEG20000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG20000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.

For research use only. We do not sell to patients.

DOPE-mPEG20000

DOPE-mPEG20000 Chemical Structure

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Other Forms of DOPE-mPEG20000:

DOPE-mPEG20000 Related Antibodies

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Description

DOPE-mPEG20000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG20000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.

In Vitro

The structure of DOPE-mPEG comprises two key components that work synergistically:
DOPE: Containing two oleoyl groups (C18:1), it imparts excellent membrane fluidity and promotes membrane fusion under acidic conditions (such as endosome escape).
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DOPE-mPEG20000 Related Antibodies
SMILES

CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COP(OCCNC(OCCOC)=O)(O)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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DOPE-mPEG20000 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DOPE-mPEG20000Biochemical Assay ReagentsInhibitorinhibitorinhibit

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HY-W440988H
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