2. GPCR/G Protein
  3. Motilin Receptor
  4. DS-3801b

DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation.

For research use only. We do not sell to patients.

DS-3801b Chemical Structure

DS-3801b Chemical Structure

CAS No. : 1369412-66-7

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 512 In-stock
Solution
10 mM * 1 mL in DMSO USD 512 In-stock
Solid
5 mg USD 500 In-stock
10 mg USD 850 In-stock
25 mg USD 1800 In-stock
50 mg USD 3000 In-stock
100 mg USD 4600 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

DS-3801b Related Antibodies

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Description

DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation[1].

Molecular Weight

465.63

Formula

C28H39N3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H]1CC[C@H](OC2=CC=CC(CO)=C2)CC1)N(C)C3=CC=C(CN4C[C@H](C)NCC4)C(C)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (214.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1476 mL 10.7381 mL 21.4763 mL
5 mM 0.4295 mL 2.1476 mL 4.2953 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1476 mL 10.7381 mL 21.4763 mL 53.6907 mL
5 mM 0.4295 mL 2.1476 mL 4.2953 mL 10.7381 mL
10 mM 0.2148 mL 1.0738 mL 2.1476 mL 5.3691 mL
15 mM 0.1432 mL 0.7159 mL 1.4318 mL 3.5794 mL
20 mM 0.1074 mL 0.5369 mL 1.0738 mL 2.6845 mL
25 mM 0.0859 mL 0.4295 mL 0.8591 mL 2.1476 mL
30 mM 0.0716 mL 0.3579 mL 0.7159 mL 1.7897 mL
40 mM 0.0537 mL 0.2685 mL 0.5369 mL 1.3423 mL
50 mM 0.0430 mL 0.2148 mL 0.4295 mL 1.0738 mL
60 mM 0.0358 mL 0.1790 mL 0.3579 mL 0.8948 mL
80 mM 0.0268 mL 0.1342 mL 0.2685 mL 0.6711 mL
100 mM 0.0215 mL 0.1074 mL 0.2148 mL 0.5369 mL
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DS-3801b Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DS-3801b1369412-66-7Motilin ReceptorMLNRGPR38gastrointestinalgastroparesischronic constipationInhibitorinhibitorinhibit

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