DuP 714
DuP 714 is an oral active thrombin inhibitor with the IC50 values of 150 nM aganist thrombin-induced aggregation in washed human platelets. DuP 714 can be used for study of arterial thrombosi.
For research use only. We do not sell to patients.
- CAS No.: 130982-43-3
- Formula: C21H33BN6O5
- Molecular Weight:460.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Odiparcilβ-D-xyloside Derivative
Biological Activity
Description
Chemical Information
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CAS No. 130982-43-3
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Molecular Weight 460.33
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Formula C21H33BN6O5
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SMILES
CC(N[C@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@H](B(O)O)CCCNC(N)=N)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Reilly TM, et al. Effect of thrombin inhibitors on platelet functions: comparative analysis of DuP 714 and hirudin. Blood Coagul Fibrinolysis. 1992;3(5):513-517. [Content Brief]
[2]. Mitchell TJ, et al. Analysis of the thrombin inhibitor DuP 714 by an enzyme-linked immunosorbent assay. Blood Coagul Fibrinolysis. 1994;5(4):517-521. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DuP 714 Related Classifications
HY-117561 Related Classifications
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