(E)-4-Stilbenol
(E)-4-Stilbenol is a hydroxylated stilbene compound and also a fungicide. (E)-4-Stilbenol inhibits the growth of Gloeophyllum trabeum and Poria placenta. (E)-4-Stilbenol is applicable to research related to fungal infections.
For research use only. We do not sell to patients.
- CAS No.: 6554-98-9
- Formula: C14H12O
- Molecular Weight:196.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
5.5 μM
Compound: 4
|
Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
|
[PMID: 26750258] |
| HEK293 | EC50 |
8.4 μM
Compound: 4
|
Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level
Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level
|
[PMID: 26750258] |
| HEK293 | IC50 |
10 μM
Compound: 4
|
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
|
[PMID: 26750258] |
| HT-29 | IC50 |
34.6 μM
Compound: 3c
|
Antiproliferative activity against human HT-29 cells after 3 days by MTT assay
Antiproliferative activity against human HT-29 cells after 3 days by MTT assay
|
[PMID: 23623255] |
In Vitro
(E)-4-Stilbenol (compound 1) inhibits mycelial growth of Gloeophyllum trabeum with an IC50 of 31 ppm, inhibits mycelial growth of Poria placenta with an IC50 of 12 ppm, and does not inhibit mycelial growth of Coriolus versicolor with an IC50 > 350 ppm[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6554-98-9
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Molecular Weight 196.25
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Formula C14H12O
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SMILES
C(=C/C1=CC=CC=C1)\C2=CC=C(O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)