(E/Z)-C2 Ceramide
(E/Z)-C2 Ceramide is a ceramide.
For research use only. We do not sell to patients.
- CAS No.: 195194-58-2
- Formula: C20H39NO3
- Molecular Weight:341.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
31.6 μM
Compound: C2-ceramide
|
In vitro growth inhibitory effect in human T-cell acute leukemia cells CCRF-CEM
In vitro growth inhibitory effect in human T-cell acute leukemia cells CCRF-CEM
|
[PMID: 11689086] |
| FL5.12 | IC50 |
33 μM
Compound: 9
|
Cytotoxicity against mouse FL5.12A cells after 48 hrs by DAPI staining-based flow cytometric analysis
Cytotoxicity against mouse FL5.12A cells after 48 hrs by DAPI staining-based flow cytometric analysis
|
[PMID: 27475534] |
| HCT-116 | EC50 |
24.5 μM
Compound: 3, C2-ceramide
|
Cytotoxicity against HCT116 cells assessed as cell survival by SRB assay
Cytotoxicity against HCT116 cells assessed as cell survival by SRB assay
|
[PMID: 17561396] |
| HepG2 | IC50 |
58 μM
Compound: 1a
|
Antiproliferative activity against human HepG2 cells after 24 hrs by Alamar blue assay
Antiproliferative activity against human HepG2 cells after 24 hrs by Alamar blue assay
|
[PMID: 25172146] |
| HL-60 | IC50 |
26 μM
Compound: 1a
|
Antiproliferative activity against human HL60 cells after 24 hrs by Alamar blue assay
Antiproliferative activity against human HL60 cells after 24 hrs by Alamar blue assay
|
[PMID: 25172146] |
| HT-29 | IC50 |
25.9 μM
Compound: C2-ceramide
|
Antiproliferative activity against human HT-29 cells measured after 72 hrs by sulforhodamine B assay
Antiproliferative activity against human HT-29 cells measured after 72 hrs by sulforhodamine B assay
|
[PMID: 33592537] |
| K562 | EC50 |
35.1 μM
Compound: 3, C2-ceramide
|
Cytotoxicity against K562 cells assessed as cell survival by MTT assay
Cytotoxicity against K562 cells assessed as cell survival by MTT assay
|
[PMID: 17561396] |
| MCF7 | IC50 |
45.41 μM
Compound: 1, C2 ceramide
|
Cytotoxicity against human MCF7 cells after 24 hrs by CellTiter-Blue assay
Cytotoxicity against human MCF7 cells after 24 hrs by CellTiter-Blue assay
|
[PMID: 19171486] |
| MDA-MB-231 | IC50 |
35.37 μM
Compound: 1, C2 ceramide
|
Cytotoxicity against human MDA-MB-231 cells after 24 hrs by CellTiter-Blue assay
Cytotoxicity against human MDA-MB-231 cells after 24 hrs by CellTiter-Blue assay
|
[PMID: 19171486] |
| NCI-H358 | EC50 |
19.6 μM
Compound: 3, C2-ceramide
|
Cytotoxicity against NCI-H358 cells assessed as cell survival by SRB assay
Cytotoxicity against NCI-H358 cells assessed as cell survival by SRB assay
|
[PMID: 17561396] |
| NHDF | IC50 |
66.5 μM
Compound: 1, C2 ceramide
|
Cytotoxicity against NHDF after 24 hrs by CellTiter-Blue assay
Cytotoxicity against NHDF after 24 hrs by CellTiter-Blue assay
|
[PMID: 19171486] |
| PC-12 | IC50 |
98 μM
Compound: 1a
|
Antiproliferative activity against rat PC12 cells after 24 hrs by Alamar blue assay
Antiproliferative activity against rat PC12 cells after 24 hrs by Alamar blue assay
|
[PMID: 25172146] |
| SK-BR-3 | IC50 |
49.2 μM
Compound: 1, C2 ceramide
|
Cytotoxicity against human SKBR3 cells after 24 hrs by CellTiter-Blue assay
Cytotoxicity against human SKBR3 cells after 24 hrs by CellTiter-Blue assay
|
[PMID: 19171486] |
Chemical Information
-
CAS No. 195194-58-2
-
Molecular Weight 341.54
-
Formula C20H39NO3
-
SMILES
[C@H]([C@@H](C=CCCCCCCCCCCCCC)O)(NC(C)=O)CO
-
Synonyms
(E/Z)-Ceramide 2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)