1. Apoptosis
  2. Apoptosis
  3. Echitamine chloride

Echitamine chloride  (Synonyms: Ditaine chloride)

Cat. No.: HY-N3797A Purity: ≥98.0%
COA Handling Instructions

Echitamine (Ditaine) chloride is the major monoterpene indole alkaloid present in Alstonia scholaris with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 μM.

For research use only. We do not sell to patients.

Echitamine chloride Chemical Structure

Echitamine chloride Chemical Structure

CAS No. : 6878-36-0

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Based on 1 publication(s) in Google Scholar

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Description

Echitamine (Ditaine) chloride is the major monoterpene indole alkaloid present in Alstonia scholaris with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 μM[1][2].

IC50 & Target

IC50: 10.92 µM (Pancreatic lipase)[2]

Molecular Weight

420.93

Formula

C22H29ClN2O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@]([C@@](C1=CC=CC=C1N2)(CC3)[C@]2([C@H]4O)[N+]3(C/C5=C/C)C)([C@H]5C4)CO)OC.[Cl-]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Echitamine chloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Echitamine chloride
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