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Cat. No.: HY-N19232

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ECO-02301

ECO-02301 is an antifungal agent identified in Streptomyces aizunensis NRRL B-11277. ECO-02301 exhibits antifungal activity against human pathogenic fungi including Candida albicans, and can be used in research related to fungal infections.

For research use only. We do not sell to patients.

CAS No.: 735316-93-5
Formula: C₇₀H₁₀₈N₂O₂₀
Molecular Weight:1297.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ECO-02301 Chemical Structure

CAS No.: 735316-93-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

ECO-02301 exhibits potent antifungal activity against a variety of human pathogenic fungi, with an MIC of 4 μg/mL against most Candida species and Saccharomyces cerevisiae, and an MIC of 16 μg/mL against Aspergillus fumigatus^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 735316-93-5
Molecular Weight 1297.61
Formula C₇₀H₁₀₈N₂O₂₀
SMILES

NCCC[C@@H](O)C[C@@H](O)C/C=C/[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)C/C=C/[C@@H](O)C[C@@H](O)C[C@@H](O)CC([C@H](C)[C@@H](O[C@@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)C)C/C=C/C=C/C=C/C=C/C=C/[C@@H]([C@H]([C@@H]([C@@H](/C=C/CC/C=C/C=C/C=C/C=C/C(NC2=C(CCC2=O)O)=O)C)O)C)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. McAlpine JB, et al. Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example. Journal of natural products. 2005 Apr;68(4):493-6. [Content Brief]

[2]. Zhang W, et al. A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis. Journal of the American Chemical Society. 2010 May 12;132(18):6402-11. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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