EN1033 (Standard)
EN1033 (Standard) is the analytical standard of EN1033 (HY-175759). This product is intended for research and analytical applications. EN1033 is a covalent immune regulatory transcription factor 5/8 (IRF5/8) molecular glue degrader. EN1033 degrades IRF5 in a proteasome-dependent manner. EN1033 engages and degrades IRF8 more robustly and rapidly. EN1033 covalently targets C28 and C223 to destabilize and degrade IRF5 and IRF8 respectively, thereby inhibiting their pro-inflammatory transcriptional activity. EN1033 serves as a promising tool for the study of autoimmune and inflammatory disorders.
For research use only. We do not sell to patients.
- CAS No.: 2193367-28-9
- Formula: C15H18N2O
- Molecular Weight:242.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2193367-28-9
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Molecular Weight 242.32
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Formula C15H18N2O
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SMILES
C=CC(N1C2=CC=CC=C2CN3C(CCC3)C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EN1033 (Standard) Related Classifications
HY-175759R Related Classifications
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Keywords
- EN1033 (Standard)
- 2193367-28-9
- Reference Standards
- Molecular Glues
- IFNAR
- Interferon-α/β receptor
- Interferon-alpha/beta receptor
- Immune regulatory transcription factor 5/8
- IRF5/8
- Pro-inflammatory transcriptional
- Autoimmune and inflammatory diseases
- cytokines
- chemokines
- covalent
- degraders
- THP1
- Inhibitor
- inhibitor
- inhibit