Encainide hydrochloride (Synonyms: MJ9067 hydrochloride)

Cat. No.: HY-12531: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Encainide (MJ9067) hydrochloride is an antiarrhythmic agent with class IC activity. Encainide has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research.

For research use only. We do not sell to patients.

Encainide hydrochloride Chemical Structure

CAS No. : 66794-74-9

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Other In-stock Forms of Encainide hydrochloride:

Other Forms of Encainide hydrochloride:

Encainide In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vivo

Encainide hydrochloride (MJ9067 hydrochloride; 0.3, 0.9, 2.7 mg/kg; infusion of single doses) prolongs His-Purkinje conduction time (HV interval) and intra-ventricular conduction time (QRS duration) but has no effect on sinus nodal recovery time or AV nodal conduction, or on refractoriness of atrium, AV node, or ventricular myocardium or on QT interval^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

388.93

Formula

C₂₂H₂₉ClN₂O₂

CAS No.

66794-74-9

Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC=CC=C1CCC2N(C)CCCC2)C3=CC=C(OC)C=C3.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 1000 mg/mL (2571.16 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5712 mL	12.8558 mL	25.7116 mL
5 mM	0.5142 mL	2.5712 mL	5.1423 mL
10 mM	0.2571 mL	1.2856 mL	2.5712 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (0 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. R N Brogden, et al. Encainide. A review of its pharmacological properties and therapeutic efficacy. Drugs. 1987 Nov;34(5):519-38. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.5712 mL	12.8558 mL	25.7116 mL	64.2789 mL
	5 mM	0.5142 mL	2.5712 mL	5.1423 mL	12.8558 mL
	10 mM	0.2571 mL	1.2856 mL	2.5712 mL	6.4279 mL
	15 mM	0.1714 mL	0.8571 mL	1.7141 mL	4.2853 mL
	20 mM	0.1286 mL	0.6428 mL	1.2856 mL	3.2139 mL
	25 mM	0.1028 mL	0.5142 mL	1.0285 mL	2.5712 mL
	30 mM	0.0857 mL	0.4285 mL	0.8571 mL	2.1426 mL
	40 mM	0.0643 mL	0.3214 mL	0.6428 mL	1.6070 mL
	50 mM	0.0514 mL	0.2571 mL	0.5142 mL	1.2856 mL
	60 mM	0.0429 mL	0.2143 mL	0.4285 mL	1.0713 mL
	80 mM	0.0321 mL	0.1607 mL	0.3214 mL	0.8035 mL
	100 mM	0.0257 mL	0.1286 mL	0.2571 mL	0.6428 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Encainide hydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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