Encainide hydrochloride
Encainide (MJ9067) hydrochloride is an antiarrhythmic agent with class IC activity. Encainide hydrochloride blocks voltage-dependent potassium channels. Encainide hydrochloride has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research.
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- CAS No.: 66794-74-9
- Formule: C22H29ClN2O2
- Masse moléculaire:388.93
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 66794-74-9
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Appearance Solid
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Masse moléculaire 388.93
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Formule C22H29ClN2O2
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Color White to off-white
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SMILES
O=C(NC1=CC=CC=C1CCC2N(C)CCCC2)C3=CC=C(OC)C=C3.[H]Cl
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Synonyms
MJ9067 hydrochloride
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
H2O : 1000 mg/mL (2571.16 mM; ultrasonic and warming and heat to 80°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (275 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. R N Brogden, et al. Encainide. A review of its pharmacological properties and therapeutic efficacy. Drugs. 1987 Nov;34(5):519-38. [Content Brief]
[2]. Hongliang Li, et al. Encainide, a class Ic anti-arrhythmic agent, blocks voltage-dependent potassium channels in coronary artery smooth muscle cells. Korean J Physiol Pharmacol. 2023 Jul 1;27(4):399-406. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.5712 mL | 12.8558 mL | 25.7116 mL | 64.2789 mL |
| 5 mM | 0.5142 mL | 2.5712 mL | 5.1423 mL | 12.8558 mL | |
| 10 mM | 0.2571 mL | 1.2856 mL | 2.5712 mL | 6.4279 mL | |
| 15 mM | 0.1714 mL | 0.8571 mL | 1.7141 mL | 4.2853 mL | |
| 20 mM | 0.1286 mL | 0.6428 mL | 1.2856 mL | 3.2139 mL | |
| 25 mM | 0.1028 mL | 0.5142 mL | 1.0285 mL | 2.5712 mL | |
| 30 mM | 0.0857 mL | 0.4285 mL | 0.8571 mL | 2.1426 mL | |
| 40 mM | 0.0643 mL | 0.3214 mL | 0.6428 mL | 1.6070 mL | |
| 50 mM | 0.0514 mL | 0.2571 mL | 0.5142 mL | 1.2856 mL | |
| 60 mM | 0.0429 mL | 0.2143 mL | 0.4285 mL | 1.0713 mL | |
| 80 mM | 0.0321 mL | 0.1607 mL | 0.3214 mL | 0.8035 mL | |
| 100 mM | 0.0257 mL | 0.1286 mL | 0.2571 mL | 0.6428 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Encainide hydrochloride Related Classifications
HY-12531 Related Classifications
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