Enfiborole
Enfiborole is an oxaborolane ester inhibitor with trypanocidal activity against parasites. Enfiborole displays IC50 values ≤ 20 nM against Trypanosoma brucei and Trypanosoma cruzi, and its IC50 against replicating trypanosomes ranges from 21 to 999 nM. Enfiborole inhibits the growth of Trypanosoma brucei, suppresses hypoxanthine incorporation in replicating trypanosomes, and inhibits the growth of Trypanosoma cruzi amastigotes. Enfiborole can be used in studies related to trypanosome infections.
For research use only. We do not sell to patients.
- CAS No.: 2152662-88-7
- Formula: C21H22BF3N2O5
- Molecular Weight:450.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Trypanosoma |
Enfiborole (6-168) potently inhibits Trypanosoma congolense growth and Trypanosoma cruzi amastigote growth with IC50 values ≤ 20 nM, and inhibits Trypanosoma vivax hypoxanthine incorporation with an IC50 in the range of 21-999 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2152662-88-7
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Molecular Weight 450.22
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Formula C21H22BF3N2O5
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SMILES
CC1=C2C(COB2O)=CC=C1C(N[C@@H](C(C)C)C(OCC3=CN=C(C(F)(F)F)C=C3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Enfiborole Related Classifications
HY-184074 Related Classifications
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