Enpatoran (Standard)
Enpatoran (Standard) is the analytical standard of Enpatoran (HY-134581). This product is intended for research and analytical applications. Enpatoran (M5049) is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran is inactive against TLR3, TLR4 and TLR9. Enpatoran can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran exhibits excellent pharmacoKinetic properties in vivo. Enpatoran can be used for both innate and adaptive autoimmunity blocKing research .
For research use only. We do not sell to patients.
- CAS No.: 2101938-42-3
- Formula: C16H15F3N4
- Molecular Weight:320.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2101938-42-3
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Molecular Weight 320.31
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Formula C16H15F3N4
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SMILES
N#CC(C=C1)=C(N=CC=C2)C2=C1N3C[C@@H](C(F)(F)F)C[C@@H](N)C3
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Synonyms
M5049 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)