EP300/CBP ligand 3
CBP/p300 ligand 11 is a ligand of EP300 and CBP, which can be used for PROTAC synthesis, such as serving as the target protein ligand of PROTAC CBP/EP300 Degrader-5 (HY-184453).
For research use only. We do not sell to patients.
- Formula: C27H28N4O3
- Molecular Weight:456.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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EP300 |
CBP |
CBP/p300 ligand 11 is the target protein ligand of PROTAC CBP/EP300 Degrader-5 (HY-184453). PROTAC CBP/EP300 Degrader-5 is a PROTAC degrader targeting CBP and EP300, which induces G1-phase cell cycle arrest and triggers apoptosis. PROTAC CBP/EP300 Degrader-5 can be used in research related to EP300-dependent malignancies[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 456.54
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Formula C27H28N4O3
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SMILES
O=C([C@@H]1N(C(C2(C3=CC=C(OCC#C)C=C3)CCCC2)=O)CCC1)NC4=CC=CC5=C4C=NN5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)